Thursday, October 22, 2009

How to Treat Inflammation



Big Pharma is now making a push that cholesterol lowering medications should be used in anyone with signs of inflammation.  The Jupitor study (NEJM.  VOl 359; 2008) looked at the use of Crestor (a statin drug) in “healthy” individuals who had elevated laboratory tests showing inflammation (via a blood test known as the CRP test).  The use of Crestor was reported to decrease CRP by 37%.  Inflammation has been thought to be the underlying cause (or one of the underlying causes) of a wide variety of illnesses including heart disease, diabetes, and arthritis.   The CRP test is a well-accepted laboratory measure of inflammation. 

Unfortunately, inflammation is occurring at epidemic rates in our society.  I routinely check my patients for inflammatory markers and I am amazed at the numbers of patients suffering from elevated inflammation markers and inflammatory diseases.

What are the signs of inflammation?  Pain, swelling, and redness are the most common signs.   A bloated abdomen, fatigue and even brain fog can be related to inflammation.  You can see that inflammatory conditions can cause a wide range of problems.  

Why do so many suffer from inflammation?  I have no doubt that diet is the main cause.  Eating a diet full of refined foods markedly increases your chances of developing inflammation.  The Standard American Diet (SAD ) ensures your body will be deficient in vital nutrients which prevent and heal inflammatory conditions.  Obese patients suffer from more inflammation as compared to non-obese patients.  Finally, failure to drink adequate amounts of water worsens any inflammatory condition. 

So, what can you do if you have signs of inflammation?   A recent study showed that Vitamin C reduced CRP by 25% versus placebo (Free Rad. Biol. and Med.   46;2009).  The authors of this study claimed that the effect of vitamin C was similar to those of statins. 

I say, take your vitamin C (2-5,000mg/day), drink adequate amounts of water and eat a diet full of unrefined foods.  This is an inexpensive way to treat or avoid getting an inflammatory condition.   Furthermore, this therapy is virtually free of adverse effects.      



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